five

Rnmt and Ram regulate the activated CD4 T cell transcriptome

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198541
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We investigated the role of RNMT and its cofactor RAM in T cells using conditional knockout mouse models. We demonstrate that RNMT and RAM have broadly overlapping roles in CD4 T cell activation. Sequencing of rRNA-depleted RNA from 20 hour activated CD4 T cells from Rnmt fl/fl CD4cre (Rnmt cKO), Rnmt fl/fl (Rnmt control), Ram fl/fl CD4cre (Ram cKO) and Ram fl/fl (Ram control) mice.
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2024-04-09
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