首页/数据集/mESCs cultured in microfluidic chambers take control of their fate by producing endogenous signals including LIF

mESCs cultured in microfluidic chambers take control of their fate by producing endogenous signals including LIF

ChEBI2015-12-18 更新2026-07-12 收录

细胞命运调控

微流控细胞培养

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-75732 数据链接链接失效反馈

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资源简介：

mESCs cultured in microfluidic chambers take control of their fate by producing endogenous signals including LIF

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创建时间：

2015-12-18

细胞命运调控

表观遗传学

Mammalian genomes contain long domains with distinct average compositions of A/T versus G/C base pairs. In a screen for proteins that might interpret base composition by binding to AT-rich motifs, we

Mendeley Data2024-03-27 更新80

The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates [ATAC-Seq]. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates [ATAC-Seq]

细胞命运调控

表观遗传

When stem cells activate a member of the SOX family of pioneer factors, they bind their cognate sequences within condensed chromatin, not only evicting the associated nucleosome, but also recruiting H

NIAID Data Ecosystem50

Oscillations of the p53-Akt Network: Implications on Cell Survival and Death

细胞命运调控

P53信号通路

Intracellular protein levels of p53 and MDM2 have been shown to oscillate in response to ionizing radiation (IR), but the physiological significance of these oscillations remains unclear. The p53-MDM2

NIAID Data Ecosystem40

Epidermal overexpression of ∆NLef1 leads to deregulation of epidermal stem cell fate

细胞命运调控

毛囊发育分子机制

In adult K14ΔNLef1 mouse, the overexpression of ∆NLef1, a B-catenin dominat negative, in basal keratinocytes leads to the conversion of hair follicles into multilayered epithelial cysts and ectopic se

NIAID Data Ecosystem60

High-efficiency cellular reprogramming with microfluidics. Homo sapiens

干细胞重编程

微流控细胞培养

We report that the efficiency of reprogramming human somatic cells to induced pluripotent stem cells (hiPSCs) can be dramatically improved in a microfluidic environment. Microliter-volume confinement

NIAID Data Ecosystem40

mESCs cultured in microfluidic chambers take control of their fate by producing endogenous signals including LIF

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