Supplementary Table S2 from The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma

XLSX file 327K, Supplementary Table S2. Mutations seen exclusively in resistant tumors. For patients with whole exome sequencing data on both pre-treatment and resistant tumors (n = 32), this table summarizes the complete set of non-synonymous mutations and short insertion/deletions called only in the resistant but not pre-treatment tumors. Alterations in this table met the additional criteria of at least 30X coverage in the tumor and an allelic fraction of at least 0.05. Each column is a patient, each row is a gene, and each non-blank entry denotes the protein change that results from the mutation.