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Effect of somatostatin knockout on sexually dimorphic hepatic gene expression

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE56520
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The liver is one of the most sexually dimorphic organs as measured by gene expression differences. About 80% of the sexually dimorphic genes are known to be regulated by growth hormone (GH). Somatostatin (SST) inhibits the release of GH. We generated a SST-knockout mouse and analyzed the hepatic gene expression changes in both sexes. We used liver samples from three mice of both sexes and somatostatin genotypes. Mouse background was C57BL/6.
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2019-02-11
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