Microarray Analyses of mRNA in lncRNA IRENA overexpressed macrophages. Microarray Analyses of mRNA in lncRNA IRENA overexpressed macrophages

LncRNAs play a critical role in both innate and adaptive immunity by regulating survival, differentiation, migration and cytokine production of the immune cells We found a cytoplasmic lncRNA IRENA in the TAMs, which triggered the NF-κB signaling and increased the production of pro-tumor inflammatory cytokines. Overall design: We comparied mRNA expression profile of IRENA overexpressed macrophages with vector group.