Table S6 from Chemogenomic Landscape of <i>RUNX1</i>-mutated AML Reveals Importance of <i>RUNX1</i> Allele Dosage in Genetics and Glucocorticoid Sensitivity
Purpose: Using RNA-sequencing, determine the effect of corticosteroids on human airway smooth muscle cells (ASM) exposed to Th1 and/or Th17 cytokines. Effects of cytokines and/or corticosteroids on ge
Values are expressed median (interquartile range) except for ratio of CI/CS. *CI (steroid insensitive; IC50dex>10−4 M) and CS (steroid sensitive IC50dex<10−4 M) as measured after anti-CD3/28/TNFα stim
Genotype data for 88 African American indviduals in binary PLINK format published in Maranville JC, Baxter SS, Witonsky DB, Chase MA, Di Rienzo A. (2013) Genetic Mapping with Multiple Levels of Phen
We used CRISPR/Cas9 to knock in the cancer "hotspot" mutation PIK3CA-H1047R into one or both alleles of a wild-type induced pluripotent stem cell (iPSC) line (WTC11; Coriell # GM25256; P37-P38). Three
Tissue sensitivity to glucocorticoids is a key factor dictating outcome of their homeostatic and therapeutic action, whereby liver represents one of the major peripheral targets. Here, we used pigs ca
