five

Effect of knocking down complex I subunit nuo-5 (ortholog of the human NDUFS1) in C.elegans

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144573
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In this study we compared the transcriptomic profile in control L3 larvae with that of mild or strong (arrested) nuo-5 RNAi. The two treatment (mild and strong) in fact lead to two very different phenotype. The mild supperssion of nuo-5 induces improved healthspand and has pro longevity effect. The strong suppression of the same gene has, on the contrary, deleterious effects such as arrested development. Three different groups were analyzed, each containing 4 independent samples
创建时间:
2022-05-25
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