Idiopathic membranous nephropathy (IMN) is an organ-specific autoimmune disease of the kidney glomerulus. It may gradually progress to end-stage renal disease (ESRD) characterized by increased protein

NIAID Data Ecosystem50

Tanshinone IIA reduces tubulointerstitial fibrosis by suppressing GSDMD-mediated pyroptosis

肾脏疾病

药物机制

Tanshinone IIA (Tan IIA), a bioactive compound derived from the traditional Chinese herb Salvia miltiorrhiza (Family Lamiaceae, Authority Bunge) , is well-known for its protective effects in var

DataCite Commons2026-01-21 更新70

Lactate metabolism and lactylation in kidney diseases: insights into mechanisms and therapeutic opportunities

肾脏疾病

乳酸代谢

The kidney is essential for lactate metabolism. Under normal conditions, the renal cortex mainly absorbs and metabolizes lactate, with minimal amounts excreted in urine. This process is part of a gluc

DataCite Commons2025-05-14 更新60

Austria Renal Registry Renal Replacement Therapy Data 2019 - ERA-EDTA

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