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Transcription profiling of fat and normal adipocytes from insulin receptor knockout mice sorted into small and large cells

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Mice with fat-specific disruption of the insulin receptor gene (FIRKO mice) have low fat mass, and are protected against obesity and obesity-related glucose intolerance. FIRKO mice also exhibit polarization of adipocytes into populations of large and small cells. Other PubMed identifiers for this study: PMID:15131120; PMID:12110165; and PMID:15131119.

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