Crystal structure of the kinase domain of human Traf2- and Nck- interacting Kinase with Wee1Chk1 inhibitor

Protein Data Bank Japan2023-12-20 更新2026-03-21 收录

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Crystal structure of the kinase domain of human Traf2- and Nck- interacting Kinase with Wee1Chk1 inhibitor Descriptor: 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, SODIUM ION, TRAF2 AND NCK-INTERACTING PROTEIN KINASE Authors: Vollmar, M, Alfano, I, Shrestha, B, Bray, J, Muniz, J.R.C, Roos, A, Filippakopoulos, P, Burgess-Brown, N, Ugochukwu, E, Gileadi, O, Phillips, C, Mahajan, P, Pike, A.C.W, Fedorov, O, Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S. Deposit date: 2010-02-26 Release date: 2010-07-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal Structure of the Kinase Domain of Human Traf2- and Nck-Interacting Kinase with Wee1Chk1 Inhibitor To be Published

人源Traf2与Nck相互作用激酶（Traf2- and Nck-interacting Kinase）激酶结构域结合Wee1Chk1抑制剂的晶体结构描述项：9-羟基-4-苯基吡咯并[3,4-C]咔唑-1,3(2H,6H)-二酮、钠离子、TRAF2与NCK相互作用蛋白激酶作者：Vollmar, M、Alfano, I、Shrestha, B、Bray, J、Muniz, J.R.C、Roos, A、Filippakopoulos, P、Burgess-Brown, N、Ugochukwu, E、Gileadi, O、Phillips, C、Mahajan, P、Pike, A.C.W、Fedorov, O、Chaikuad, A、von Delft, F、Bountra, C、Arrowsmith, C.H、Weigelt, J、Edwards, A、Knapp, S 提交日期：2010年2月26日发布日期：2010年7月14日最后修改日期：2023年12月20日实验方法：X射线衍射（分辨率2.8埃）引用说明：《人源Traf2与Nck相互作用激酶激酶结构域结合Wee1Chk1抑制剂的晶体结构》（待发表）

创建时间：

2010-02-26