GOLD Depression Study
收藏DataCite Commons2024-11-06 更新2024-07-13 收录
下载链接：
https://datashare.ed.ac.uk/handle/10283/8525
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资源简介：
Inflammation has been linked to depression in the general population. People living with HIV are at three times greater risk for depression, and experience elevated inflammation despite antiretroviral therapy. We investigated whether inflammatory biomarkers in the brain and the blood may mediate the association between HIV status and depressive symptoms. We recruited 60 young people living with and without HIV in Cape Town, South Africa. Participants completed the nine-item Patient Health Questionnaire (PHQ-9) as a measure of depressive symptoms, underwent magnetic resonance spectroscopy to quantify choline and myo-inositol in three brain regions, and provided a blood serum sample in which we quantified concentrations of blood biomarkers of inflammation and neurogenesis.
提供机构：
University of Edinburgh. Edinburgh Neuroscience
创建时间：
2023-08-30
