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EPI-Clone dataset: Mature cell experiment

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DataCite Commons2025-06-01 更新2024-08-19 收录
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https://figshare.com/articles/dataset/EPI-Clone_dataset_Mature_cell_experiment/25472467/1
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This is the dataset supporting the EPI-Clone manuscript: Targeted single cell methylation profiling of hematopoietic stem and progenitor cells (HSPCs) and mature myeloid cells from blood, bone marrow, and lung was performed with the scTAMseq method. Two experiments are included: Mature myeloid cells from lung tissue and HSPCs and mature myeloid cells from blood and bone marrow. Dataset is a seurat (v4) object with the following assays, reductions and metadata:  <br><b>ASSAYS</b>: AB: Antibody expression data DNAm: DNA methylation data, containing binary observations (0: amplicon not observed, i.e. dropout or absence of DNA methylation, 1: amplicon observed, i.e. DNA methylation). See the paper on scTAMseq <b>DIMENSIONALITY REDUCTION</b><b> </b>pca: PCA performed on the DNAm data umap: UMAP computed on the DNAm data <b>METADATA</b> Sample: The experiment that the cell is from, values are "Lung" for cells obtained from lung and “MyeLym” for HSPCs/mature myeloid cells from bone marrow and blood CellType: Cell type annotation LARRY: Error corrected LARRY barcode Pseudotime: Differentiation pseudotime PerformanceNonHhaI: Performance of the control amplicons in that cell TotalCounts: Number of reads on the Non-HhaI control amplicons
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figshare
创建时间:
2024-03-25
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