Performance of different approaches to the estimation of the number of different haplotypes based on simulated data.

A total of n = 5000 profiles were sampled from the coalescent for varying θ ( = 2Eμ where μ is the mutation rate per gene per generation and E the effective population size). The column ‘N’ gives the number of different haplotypes in this sample, the quantity to be estimated. The column ‘Sample’ shows the sample sizes used. Next follows the estimators , and . D gives the number of different observed haplotypes and is followed by the coverage estimate.