Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12

Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12 Descriptor: [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3,4-bis(oxidanyl)oxan-2-yl] hydrogen phosphate, dTDP-4-amino-4,6-dideoxygalactose transaminase Authors: Wang, F, Singh, S, Cao, H, Xu, W, Miller, M.D, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) Deposit date: 2015-04-13 Release date: 2015-04-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. Acs Chem.Biol., 10, 2015

来自大肠杆菌（Escherichia coli）K-12的糖氨基转移酶（sugar aminotransferase）WecE与外部醛亚胺VII（External Aldimine VII）的复合物晶体结构
描述：[(2R,3S,5R)-5-[5-甲基-2,4-二氧代嘧啶-1-基]-3-羟基-四氢呋喃-2-基]甲氧基-羟基-磷酰基 [(2R,3R,4S,5R,6R)-6-甲基-5-[(E)-[2-甲基-3-羟基-5-(膦酰氧基甲基)吡啶-4-基]亚甲基氨基]-3,4-二羟基四氢吡喃-2-基] 磷酸氢酯、dTDP-4-氨基-4,6-二脱氧半乳糖转氨酶（dTDP-4-amino-4,6-dideoxygalactose transaminase）
作者：Wang, F, Singh, S, Cao, H, Xu, W, Miller, M.D, Thorson, J.S, Phillips Jr, G.N
天然产物生物合成酶发现项目（NatPro）
提交日期：2015-04-13
发布日期：2015-04-29
最后修改日期：2023-09-27
检测方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.24埃）
引用文献：《核苷酸糖氨基转移酶（nucleotide sugar aminotransferases）中胺基安装的立体化学控制结构基础》，发表于Acs Chem.Biol.，第10卷，2015年