Transcellular transport and the effect of elacridar on uric acid transport in Caco-2 cells.
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Transcellular transport of uric acid in Caco-2 monolayer was measured in the absence or presence of elacridar (2 µM), Ko143 (1 µM), verapamil (100 µM) and MK571 (10 µM) at 37°C and pH 7.4. The ratio was obtained by dividing BL-to-AP permeability by AP-to-BL permeability. The values indicate mean ± S.E.M. (n = 3). An asterisk (*) and shows a significant difference from the control by Student's t-test (p
创建时间：
2015-12-02
