Metadata record for the manuscript: Characterization of Weaning-Induced Breast Involution in Women: Implications for Young Women’s Breast Cancer

Summary

This metadata record provides details of the data supporting the claims
of the related manuscript “Characterization of Weaning-Induced Breast
Involution in Women: Implications for Young Women’s Breast Cancer”. The data
consist of 37 .svs (ScanScope Virtual Slide; Aperio format) files and 2 summary
Excel .xlsx format spreadsheets. The related study investigated the hypothesis
that weaning-induced involution is a transient window of increased breast
cancer risk that might be mitigated by non-steroidal anti-inflammatory
treatment targeted to the ~3 month post-wean window of active tissue
remodeling.

Data access

The data generated and/or analysed during the related study are available
as part of this figshare record. The H&E stained images are the files with
.svs extensions, and are labelled according to which figure they are associated
with. Additionally, the spreadsheet “Data summary form.xlsx” lists all the .svs
files. The spreadsheet “V6 summary sheet_MOM paperchecked2.xlsx” contains the
plot data for the figures in the manuscript. Finally, the clinical data
regarding lactation history has associated PHI information along with other
clinical annotations. The lactation data will be made available on reasonable
request to the corresponding authors.

For all data requests please contact:
Pepper Schedin, PhD
Professor Department of Cell, Developmental and Cancer Biology
2720 SW Moody Ave.,
Mailing Code: KR-CDCB,
Portland, OR, 97201, USA
Office: 503-494-9341
[e-mail]

Name of Institutional Review
Board or ethics committee that approved the study

IRB approval for collection and analysis of human tissues was obtained
from the University of Colorado Institutional Review Board. Tissue provided
from the Komen Tissue Bank was analyzed under approval from Indiana University
Institutional Review Board.