Western blot PrPres immunoreactivity profiles for the Canadian BSE cases.

When using N-terminal-specific, C-terminal-specific and core-specific antibodies to compare their affinity to the different types of BSE, N-terminal-specific antibodies P4, 12B2 and SAF32 bound to all three bands of PrPres in H-type, but not to the PrPres bands of the C- or L-type cases. The core- and C-terminal-specific antibodies 9A2, L42, 6H4, 94B4, SAF84 bound to all three bands of the PrPres of the H-, L-, and C-types.****All three bands of PrPres were visible and strongly reactive;***All three bands of PrPres were visible;**Two of the three bands of PrPres were visible;*One of the three bands of PrPres was visible; - None of the PrPres bands were visible; Ab = Primary antibody.