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An Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes

ChEBI2013-03-26 更新2026-07-21 收录

生殖细胞发育

piRNA调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-44690 数据链接链接失效反馈

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资源简介：

An Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes

应用场景：

创建时间：

2013-03-26

生殖细胞发育

体外模型

Human primordial germ cells (hPGCs) are the embryonic precursors of sperm and eggs. While the exact temporal window of hPGC specification and the cellular identity of their precursors remains unclear,

NIAID Data Ecosystem40

Single-Cell Transcriptome Analysis of Rb1 Conditional Knockout Prospermatogonia

单细胞转录组学

生殖细胞发育

Prospermatogonia, precursors to the mature male germline, undergo a period of sustained quiescence during late fetal and early postnatal development. The purpose of this mitotic arrest is not fully un

NIAID Data Ecosystem20

CDK2 kinase activity is a regulator of male germ cell fate

生殖细胞发育

酶活性调控

The ability of men to remain fertile throughout their lives depends upon establishment of a spermatogonial stem cell (SSC) pool from gonocyte progenitors, and also maintaining the proper balance betwe

NIAID Data Ecosystem00

DAZL targets in undifferentiated spermatogonia

生殖细胞发育

蛋白质-RNA相互作用

DAZL's targets were identified via iCLIP in postnatal testes synchronized for undifferentiated spermatogonia. Spermatogenesis in postnatal testes was chemically synchronized to obtain testes enriched

NIAID Data Ecosystem30

Data for: Heavy ion radiation-induced DNA damage mediates apoptosis via Rpl27a-Rpl5-MDM2-p53/E2F1 signaling pathway in mouse spermatogonia

生殖细胞发育

信号通路

A total of 360 differential proteins were identified; 90 were upregulated and 270 were downregulated. A total of 101 differential mRNAs were identified; 46 were upregulated and 55 were downregulated.

NIAID Data Ecosystem10

An Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes

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