Full Factorial Design of Experiment dataset of Silk Fibroin alkaly degumming

Silk fibroin is the structural fiber of the silk filament and it is usually separated from the external fibroin by a chemical process called degumming. This process consists in an alkali bath in which the silk cocoons are boiled for a determined time. It is also known that the degumming process impacts the property of the outcoming silk fibroin fibers. In this work we present the dataset obtained from a Design of Experiment (DoE) screening made on the alkali degumming and wich results were publisced ACS biomaterials science and Engineering (https://doi.org/10.1021/acsbiomaterials.0c01657). Four process factors were considered: the number of degumming baths, the process time, the process temperature and the salt concentration. The properties of the silk fibroin fibers were studied. In particular the molecular weight was obtained by gel permeation chromatography (GPC), the mechanical data by tensile test, the secondary structure by Fourier infrared spectroscopy (FTIR).

桑蚕丝蛋白纤维是蚕丝丝胶的结构纤维，通常通过一种称为脱胶的化学过程将其与外层丝胶分离。此过程涉及将蚕茧置于一定时间的碱性浴中煮沸。众所周知，脱胶过程会对所获得的丝蛋白纤维的性能产生影响。在本研究中，我们展示了通过实验设计（DoE）筛选获得的实验数据集，相关结果已发表于《ACS生物材料科学与工程》期刊（https://doi.org/10.1021/acsbiomaterials.0c01657）。本研究考虑了四个工艺因素：脱胶浴的次数、工艺时间、工艺温度和盐浓度。对丝蛋白纤维的性能进行了研究。特别是，通过凝胶渗透色谱（GPC）获得了分子量，通过拉伸试验获得了力学数据，通过傅里叶变换红外光谱（FTIR）获得了二级结构。