Crystal structure of the catalytic domain of PPIP5K2 in complex with AMPPNP and 5-PA-InsP5
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Crystal structure of the catalytic domain of PPIP5K2 in complex with AMPPNP and 5-PA-InsP5 Descriptor: (2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}ethyl)phosphonic acid, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, MAGNESIUM ION, ... Authors: Wang, H, Shears, S.B. Deposit date: 2013-12-12 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery. Chem.Biol., 21, 2014
PPIP5K2催化结构域与AMPPNP及5-PA-InsP5复合物的晶体结构
描述组分：(2-氧代-2-{[(1S,2R,3S,4S,5R,6S)-2,3,4,5,6-五(膦酰氧基)环己基]氧基}乙基)膦酸、肌醇六磷酸(inositol hexakisphosphate)、二磷酸肌醇五磷酸激酶2(diphosphoinositol-pentakisphosphate kinase 2, PPIP5K2)、镁离子(magnesium ion)……
作者：Wang, H、Shears, S.B.
存储日期：2013-12-12
发布日期：2014-04-02
最后修改日期：2023-09-20
实验方法：X射线衍射(X-RAY DIFFRACTION)，分辨率2 Å
引用文献：《合成肌醇磷酸类似物揭示PPIP5K2具有可作为药物发现靶点的表面锚定底物结合位点》，《Chem.Biol.》，第21卷，2014年
创建时间：
2013-12-12
