A Neutral Flavin–Triphenylamine Probe for Mitochondrial Bioimaging under Different Microenvironments

A bioinspired
design built around a neutral flavin–triphenylamine
core has been investigated for selective mitochondrial bioimaging
capabilities in different microenvironments. Significant advantages
with respect to long-term tracking, faster internalization, penetrability
within the spheroid structures, and strong emission signal under induced
hypoxia conditions have been observed, which could offer an alternative
to the existing mitotrackers for hypoxia-related biological events.