Regulation of Ptch1 expression in the limb
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE52939
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资源简介：
Ptch1 is a critical negative feedback regulator of the Hedgehog signaling and is upregulated in response to pathway activation. How tissue specific responses are mediated remains unknown. Here, we performed ChIP-seq analysis for epitope-tagged endogenous Gli3 protein to identify limb-specific binding regions within the 500 kb region surrounding Ptch1. ChIP was carried out using an endogenously FLAG-tagged Gli3 protein.
创建时间：
2019-05-15
