Olfactory receptor accessory proteins play crucial roles in receptor gene choice
收藏Alliance of Genome Resources2026-08-01 收录
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Mice with olfactory accessory protein RTP1 and RTP2 knocked out show severe bias in their olfactory receptor repertoire. Surprisingly, even though RTP1,2(-/-) animals have fewer OSNs, we discovered ~8% of the ORs are expressed in larger numbers than the wild type. RNA-Seq in RTP1/2 dKO vs wild type mice olfactory epithelium
