tRNA-guanine Transglycosylase (TGT) labeled with 5-fluorotryptophan in co-crystallized complex with 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
收藏Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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tRNA-guanine Transglycosylase (TGT) labeled with 5-fluorotryptophan in co-crystallized complex with 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one Descriptor: 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, CHLORIDE ION, GLYCEROL, ... Authors: Nguyen, A, Heine, A, Klebe, G. Deposit date: 2020-03-28 Release date: 2020-04-08 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Co-crystallization, nanoESI-MS and 19F NMR reveal dimer disturbing inhibitors and conformational changes at dimer contacts To Be Published
标记有5-氟色氨酸的tRNA-鸟嘌呤转糖基酶（TGT）与2-(甲氨基)-1,7-二氢-8H-咪唑并[4,5-g]喹唑啉-8-酮形成的共结晶复合物
描述符：2-(甲氨基)-1,7-二氢-8H-咪唑并[4,5-g]喹唑啉-8-酮、氯离子、甘油……
作者：Nguyen, A、Heine, A、Klebe, G.
提交日期：2020-03-28
发布日期：2020-04-08
最后修改日期：2024-01-24
实验方法：X射线衍射（1.19 Å）
引用文献：共结晶法、纳米电喷雾电离质谱与氟-19核磁共振揭示破坏二聚体的抑制剂及二聚体接触界面的构象变化（待发表）
创建时间：
2020-03-28
