Computer-Delivered Motivational Intervention to Prevent Adherence Problems Among Youth Newly Recommended for HIV Medications: Project MESA (Motivational Enhancement System for Adherence)

A two-phase study with the primary objective of adapting and piloting Motivational Enhancement System for Adherence (MESA), a brief, two-session, computer-based motivational intervention to prevent adherence difficulties among youth newly recommended to begin HAART. Phase I pre-tested the feasibility and acceptability of the beta version of MESA with Motivational Enhancement System for Health (MESH), a nutrition and exercise control intervention. Following analysis of Phase I responses and further modification of the intervention, Phase II (a pilot randomized controlled trial) was initiated. Phase II tested a two-session MESA intervention, as well as MESH (the attention control), matched for dose and delivery format.