Role of SREBP1 in chronic endometritis
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP535100
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资源简介：
The aim of this study was to investigate the role of SREBP1a in the regulation of inflammation in endometrial tissue after LPS injection. We report that systemic deletion of Srebf1, which encodes SREBP1, resulted in persistent endometrial inflammation and CD138-positive plasma cell infiltration. In addition, Srebf1 knockout mice exhibited pregnancy loss and placental insufficiency in the endometritis model. Overall design: mRNA profiles of endometrial tissue obtained from WT and Srebf1 knockout mice 7 days after LPS-induced inflammation were analyzed.
创建时间：
2025-06-27
