Identification of differentially expressed mRNAs in HCSC cell lines compared with HCC cell lines

Name: Identification of differentially expressed mRNAs in HCSC cell lines compared with HCC cell lines
Creator: Eastern Hepatobiliary Surgery Hospital
Published: 2022-02-20T00:00:00+08:00

干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录

肝癌研究

分子生物学

数据链接：

http://data.iscr.ac.cn/Article?id=88fc1c84ad148543d36504a2119e2d85 数据链接链接失效反馈

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资源简介：

Hep3B and Huh7 are two types of human hepatoma cell lines (HCC). In our laboratory, we cultured their stem-like cancer cells (HCSCs), Hep3B-C and Huh7-C. And we have demonstrated that these cells had enhanced stem cell properties, drug resistance, properties of EMT, and stronger tumor-initiating capabilities. To explore functionally crucial mRNAs in HCSCs, 2 samples of HCSCs and 2 samples of HCCs were sequenced by the Illumina Genome Analyzer II. Through differential expression analysis, we finally identified 115 up- and 402 down-regulated miRNAs which were consistently up- and down-regulated in two stem cells compared to the cancer cells.

提供机构：

Eastern Hepatobiliary Surgery Hospital

创建时间：

2022-02-20