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Gauging Lipid Vulnerabilities in mRNA-LNPs Under Various Environmental Stressors Through TIMS-TOF Analysis

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NIAID Data Ecosystem2026-05-10 收录
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https://www.omicsdi.org/dataset/jpost/PXD075449
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资源简介:
Mass spectrometry lipidomics dataset analyzing degradation pathways of ionizable lipids in mRNA lipid nanoparticles (LNPs) exposed to environmental stressors. UHPLC–TIMS-TOF MS was used to characterize lipid oxidation products and structural degradation of DLin-MC3-DMA (MC3), SM-102, and ALC-0315 under UV irradiation, oxidative conditions, thermal exposure, and freeze–thaw cycling.
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2026-03-16
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