Intracranial EEG (iEEG) Recording in a Rat Model of Epilepsy

This database, collected at the Neural Engineering Laboratory, Iran University of Science and Technology, comprises iEEG recordings from Wistar rats during healthy and epileptic conditions. Recordings were collected from 5 rats (3 males, 2 females, weighing 260-378 g and aged 4-5 months). iEEG signals were recorded from 3 brain sites: motor cortex (left M1), thalamus (left ANT), and hippocampus (right CA1) of freely moving rats. As a result, for each rat, a matrix with 3 columns (representing the 3 signals) is available in this dataset.To induce temporal lobe epilepsy (TLE), a nonconvulsive pentylenetetrazol (PTZ) model was used. In this epileptic model, rats displayed recurrent spontaneous seizures at Racin stage 1-2, accompanied by spike-wave discharges (SWDs). A seizure can be detected by identifying high-amplitude, repetitive SWDs in the epileptic signals.Recordings were conducted in two conditions: the healthy condition (before PTZ injection) and the epileptic condition (after PTZ injection). Each healthy and epileptic condition contains several trials.The details of recording and experimental methods can be seen in the paper:Azam Ghanaei and Abbas Erfanian, ''Real-time Seizure Prediction Using Nonlinear Dynamical Analysis of Intracranial EEG and Deep Learning in a Rodent Model of Epilepsy,'' Submitted to IEEE trans. Biomed. Eng. 2025.