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Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq]

ChEBI2015-07-15 更新2026-07-12 收录

RNA剪接调控

RNA加工机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60391 数据链接链接失效反馈

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资源简介：

Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq]

应用场景：

创建时间：

2015-07-15

剪接保真度

RNA剪接调控

Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that

Alliance of Genome Resources40

Glucose dissociates DDX21 dimers to regulate mRNA processing and promote epidermal differentiation (RNA-Seq II)

RNA剪接调控

表皮细胞分化

Glucose is an important cellular energy source, however, glucose's function as a second messenger remains relatively unexplored. Here, we find that glucose binds directly to DDX21 to regulate its func

NIAID Data Ecosystem30

The transcriptional repressor, BCL11A, promotes breast cancer metastasis

癌症转移机制

RNA剪接调控

Identification of the BCL11A-regulated transcriptome and spliceosome and determination of MBNL1-dependent splicing changes by RNA-Seq Two/Three replicates were analyzed for each experimental condition

NIAID Data Ecosystem20

ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing

RNA剪接调控

神经元mRNA处理

ELAV/Hu factors are conserved RNA binding proteins that play diverse roles in mRNA processing and regulation. The founding member, Drosophila Elav, was recognized as a vital neural factor 35 years ago

NIAID Data Ecosystem40

Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency [RNA-Seq]

RNA剪接调控

RNA定位

Nuclear speckles, a type of membraneless nuclear organelle in higher eukaryotic cells, play a vital role in gene expression regulation. Using the reverse transcription-based RBP binding sites sequenci

NIAID Data Ecosystem20

Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq]

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