Mycobacterium bovis MB894 Genome sequencing and assembly

Mycobacterium bovis is the causative agent of tuberculosis (TB) in cattle, a disease that accounts for economic losses and animal welfare. It also supposes a threat to public health since M. bovis can infect humans. There is increasing evidence supporting that genetic variation among mycobacterial isolates contributes to differences in immune response induction and disease progression, and this variation in the pathogenicity of MTBC strains is probably caused by the diversity in genetic and evolutionary background. In order to identify genomic features that could explain the pathogenic phenotype observed in animal models and experimental infection (Cuerda et al 2022) we performed whole genome sequencing of MB894.