Human Dipeptidyl Peptidase IV (DPP4) with piperidine-constrained phenethylamine
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Human Dipeptidyl Peptidase IV (DPP4) with piperidine-constrained phenethylamine Descriptor: (3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) Authors: Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D. Deposit date: 2007-02-01 Release date: 2007-04-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors. J.Med.Chem., 50, 2007
人二肽基肽酶IV（Dipeptidyl Peptidase IV, DPP4）结合哌啶约束型苯乙胺类配体，配体描述：(3R,4R)-1-{6-[3-(甲磺基)苯基]嘧啶-4-基}-4-(2,4,5-三氟苯基)哌啶-3-胺；二肽基肽酶4（二肽基肽酶IV，DPP IV）。作者：Pei Z、Li X、von Geldern T.W、Longenecker K.L、Pireh D、Stewart K.D。入库日期：2007-02-01；发布日期：2007-04-24；最后修改日期：2024-10-16。检测方法：X射线衍射（分辨率2.8 Å）。引用文献：《哌啶酮与哌啶约束型苯乙胺类新型强效选择性二肽基肽酶IV抑制剂的发现及其构效关系》，《药物化学杂志》（J.Med.Chem.），第50卷，2007年
创建时间：
2007-02-01
