SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE121117
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We performed RNA sequencing analysis using NextSeq500 to identify drivers that mediate feedback RAS activation in BRAF(V600E) cells that are SHP2 independent. mRNA expression of three BRAF (V600E) cancer cells was examined before and after treatment with vemurafenib (RAF inhibitor) using NextSeq500
创建时间:
2019-03-26



