MOESM4 of Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells

Additional file 4: Table S4. Target- and substitution-specific mutations among all 19 subjects. Target- and substitution-specific mutations among all 19 subjects. Mutation number and prevalence for each substitution type with mutation prevalence (mutations/target bp/subject) in parentheses. Mutations were identified as VAF (variant allele reads/total reads) > 5 × 10− 4 (0.05%) and significantly above IS background VAF at respective site based on contingency table analysis (see Methods).