Platinum-based drugs are potent anticancer drugs and are effective for the treatment of various cancers. However, they are limited pharmacologically due to toxic side effects, drug resistance and poor
Shown are mean values calculated from at least three experiments ± SD. The cytotoxicity values (CC50) were for Hela H cells 8.54 ± 0.42 μM, for Hela R19 cells 7.07 ± 0.38 μM, and for RD, BGM, and Vero
a% micronuclei in binucleated cells.bstatistically significant by ANOVA followed by Dunn’s post hoc test (pcstatistically significant by ANOVA followed by Dunnett’s post hoc test (pdata are mean ±SD.