Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor

Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor Descriptor: 5-bromo-N-(diphenylmethyl)-N-methylthiophene-2-carboxamide, Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE Authors: Halabelian, L, Zeng, H, Dong, A, Schapira, M, De Freitas, R.F, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC) Deposit date: 2020-03-25 Release date: 2020-09-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor to be published

人类蛋白质精氨酸N-甲基转移酶6（Protein arginine N-methyltransferase 6，PRMT6）与MT2739抑制剂结合的晶体结构。抑制剂描述符：5-溴-N-(二苯甲基)-N-甲基噻吩-2-甲酰胺、蛋白质精氨酸N-甲基转移酶6、S-腺苷-L-同型半胱氨酸（S-ADENOSYL-L-HOMOCYSTEINE）。作者：Halabelian L、Zeng H、Dong A、Schapira M、De Freitas RF、Hutchinson A、Seitova A、Bountra C、Edwards AM、Arrowsmith CH、Brown PJ，以及结构基因组学联盟（Structural Genomics Consortium, SGC）。提交日期：2020-03-25；发布日期：2020-09-02；最后修改日期：2024-11-20。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.45 Å。引用信息：《人类蛋白质精氨酸N-甲基转移酶6（PRMT6）与MT2739抑制剂结合的晶体结构》，待发表。