Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal

Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal Descriptor: (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol, Glycogen phosphorylase, muscle form, ... Authors: Chrysina, E.D, Kosmopoulou, M.N, Leonidas, D.D, Oikonomakos, N.G. Deposit date: 2005-12-16 Release date: 2006-12-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.03 Å) Cite: In the Search of Glycogen Phosphorylase Inhibitors: Synthesis of C-D-Glycopyranosylbenzo(hydro)quinones Inhibition of and Binding to Glycogen Phosphorylase in the Crystal Eur.J.Org.Chem., 4, 2007

C-D-吡喃葡萄糖基氢醌与C-D-吡喃葡萄糖基苯醌的合成、蛋白酪氨酸磷酸酶1B（PTP1B）抑制活性，以及晶体状态下糖原磷酸化酶的抑制与结合作用。数据集描述项：(1S)-1,5-脱水-1-(2,5-二羟基苯基)-D-葡萄糖醇、肌肉型糖原磷酸化酶等。作者：Chrysina E.D、Kosmopoulou M.N、Leonidas D.D、Oikonomakos N.G。提交日期：2005-12-16；发布日期：2006-12-19；最后修改日期：2023-08-30。实验方法：X射线衍射（X-RAY DIFFRACTION，2.03埃）。引用文献：《探寻糖原磷酸化酶抑制剂：C-D-吡喃葡萄糖基苯(氢)醌的合成及其晶体中与糖原磷酸化酶的结合与抑制活性》，发表于《欧洲有机化学杂志》（Eur. J. Org. Chem.），2007年第4卷。