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Degranulation of NK cells and cytotoxic proteins expression post knockout of demethylases

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NIAID Data Ecosystem2026-05-01 收录
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http://flowrepository.org/id/FR-FCM-Z6LB
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m6A levels were altered in primary NK cells by knocking out/down the m6A erasers (FTO & ALKBH5), individually, using CRISPR-based Genome Editing. The demethylase-KO NK cells were analyzed for cell NKG2D, PRF1 and TRAIL protein expression levels using flow cytometry. NK cells degranulation were measured in ALKBH5 or FTO- transfected NK cells.
创建时间:
2023-07-01
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