Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to progesterone and harboring the S810L mutation responsible for a severe form of hypertension
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Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to progesterone and harboring the S810L mutation responsible for a severe form of hypertension Descriptor: Mineralocorticoid receptor, PROGESTERONE Authors: Fagart, J, Huyet, J, Pinon, G.M, Rochel, M, Mayer, C, Rafestin-Oblin, M.E. Deposit date: 2004-12-17 Release date: 2005-05-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension Nat.Struct.Mol.Biol., 12, 2005
人源盐皮质激素受体(mineralocorticoid receptor)配体结合域与孕酮结合,且携带可引发重症高血压的S810L突变的晶体结构。
描述符:盐皮质激素受体(mineralocorticoid receptor)、孕酮(PROGESTERONE)
作者:Fagart, J、Huyet, J、Pinon, G.M、Rochel, M、Mayer, C、Rafestin-Oblin, M.E.
提交日期:2004-12-17
发布日期:2005-05-24
最后修改日期:2023-08-23
实验方法:X射线衍射(X-RAY DIFFRACTION,分辨率2.34 Å)
引用:《引发高血压的突变型盐皮质激素受体的晶体结构》,发表于《自然结构与分子生物学》(Nat.Struct.Mol.Biol.),第12卷,2005年
创建时间:
2004-12-17



