Asprosin is positively associated with metabolic syndrome in hemodialysis patients: a cross-sectional study

Metabolic syndrome (MS) has a high prevalence in hemodialysis patients. High asprosin levels are associated with the accumulation of adiposity and an increase in body weight, which may drive the development of this syndrome. The relationship between asprosin and MS in patients on hemodialysis has not been investigated. We enrolled hemodialysis patients at the hemodialysis center of one hospital in May 2021. MS was defined by the International Diabetes Federation. Fasting serum asprosin levels were measured. ROC curve, multivariate logistic regression and Spearman’s rank correlation analyses were performed. In total, 134 patients were included, with 51 with MS and 83 without MS. Among the patients with MS, there was a significantly higher proportion of women (54.9%), prevalence of DM (p p p p p p p p p p p for trend Fasting serum asprosin is positively correlated with MS and could be an independent risk factor for MS in hemodialysis patients.