Human MTHFD2 in complex with Compound 1
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Human MTHFD2 in complex with Compound 1 Descriptor: 5-(4-oxo-2-phenyl-1,5,7,8-tetrahydropyrido[4,3-d]pyrimidine-6(4H)-carbonyl)-1,3-dihydro-2H-2lambda~6~,1-benzothiazole-2,2-dione, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, ... Authors: Suzuki, M, Matsui, Y, Matsuhashi, N, Kawai, J. Deposit date: 2019-02-20 Release date: 2019-06-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold. Acs Med.Chem.Lett., 10, 2019
创建时间:
2019-02-20



