BIOGRID CURATED DATA FOR NUP116 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for NUP116 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier; forms a stable association with Nup82p, Gle2p and two other FG-nucleoporins (Nsp1p and Nup159p); NUP116 has a paralog, NUP100, that arose from the whole genome duplication

NUP116（酿酒酵母S288c）蛋白质-蛋白质、遗传和化学相互作用数据集，由BioGRID（https://thebiogrid.org）精心整理；定义：FG-核孔复合体中央核心的核孔蛋白组分；直接参与核质转运以及维持核孔复合体（NPC）的通透性屏障；与Nup82p、Gle2p及另外两种FG-核孔蛋白（Nsp1p和Nup159p）形成稳定的结合；NUP116具有一个同源蛋白NUP100，该蛋白起源于全基因组复制。