Whole genome SNP discovery in 5-FU resistant mutants.
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*Experimental validation of SNP variants was performed using PCR-directed sequencing using appropriate pairs of primers (see Table S1, Supplementary Material). Following SNP validation, the WT version of each mutated gene indicated in bold were transfected in the L. infantum 263 WT, Lin5FU500.3, Lin5FU500.4 and Lin5FU500.5 strains. SNPs in italic indicate silent mutations. M, mutation; E, sequencing error; ND, not determined.
创建时间：
2015-12-02
