首页/数据集/The Chd4 helicase regulates chromatin accessibility and gene expression critical for β-cell function in vivo.

The Chd4 helicase regulates chromatin accessibility and gene expression critical for β-cell function in vivo.

NIAID Data Ecosystem2026-05-10 收录

细胞功能调控

染色质可及性

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE217446 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-09-18

染色质可及性

脑源因子调控

Brain-Derived Neurotrophic Factor (BDNF) is crucial for neuronal survival, differentiation, synaptic plasticity, memory formation, and neurocognitive health. Molecular mechanisms of BDNF promoting cel

NIAID Data Ecosystem80

Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling [HeLa ATAC-Seq]

染色质可及性

先天免疫信号抑制

The Tousled like kinases 1 and 2 (TLK1/2) control histone deposition through the ASF1 histone chaperones and are regulated by the DNA damage response. Depletion of TLK activity caused replication stre

NIAID Data Ecosystem40

Effect of chronic epinephrine exposure on gene expression in MIN6 cells

细胞功能调控

激素转录组学

Chronic exposure to epinephrine enhances the compensatory insulin secretion in MIN6 cells while persistently inhibiting cell proliferation. The molecular mechanisms underlying these phenomena were inv

NIAID Data Ecosystem30

DNase-seq from posterior cingulate gyrus (ENCSR503UFM)

染色质可及性

功能基因组学

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

NIAID Data Ecosystem50

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

免疫逃逸机制

细胞功能调控

Immune evasion is now recognized as a key feature of cancer progression. In animal models, the activity of cytotoxic lymphocytes is suppressed in the tumour microenvironment by the immunosuppressive c

Figshare2016-01-18 更新40

The Chd4 helicase regulates chromatin accessibility and gene expression critical for β-cell function in vivo.

资源简介：

相关数据集