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Attachment and Growth of Human Rotaviruses RV-3 and S12/85 in Caco-2 Cells Depend on VP4

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PubMed Central2026-05-16 收录
下载链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC110359/
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资源简介:
Studies with human neonatal rotaviruses RV-3 and S12/85 and their reassortants showed that VP4 is a determinant of rotavirus attachment to and growth in Caco-2 cells. The binding of these viruses to MA104 and Caco-2 cells correlated with their growth ability. Virus sensitivity to trypsin and the VP4 fusion region may be implicated in these processes.
提供机构:
American Society for Microbiology (ASM)
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