Differential gene expression in miR-146a-/- vs. WT hematopoietic stem and progenitor cells [miR146aKO_vs_WT_RNA-seq_bulk]
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=f67112c6db8d24f9a596a500016e1b12
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资源简介：
To identify pathways and processes driving the observed hematopoietic stem cell (HSC) aging-like phenotypes in miR-146a-/- vs. WT, we performed RNA-seq gene expression profiling of Lin- Sca-1+ c-Kit+ (LSK) cells isolated from miR-146a-/- or WT mouse bone marrow (BM). Differential expression analysis and EnrichmentMap network analysis identified cytokine signalling and immune pathways as potential drivers of aging-like alterations in miR-146a-/- HSC proliferation and differentiation.
提供机构：
BC Genome Science Centre
创建时间：
2022-02-20
