Isoflurane anesthesia disrupts the cortical metabolome

Table 1 Descriptive statistics for 61 metabolites from mouse prefrontal cortex measured during both wakefulness and isoflurane anesthesia. Columns give median, maximum, and minimum values, unadjusted mixed model ANOVA p-values, and Benjamini Hochberg FDR adjusted q-values
Table 2 Metabolites detected only during wakefulness or only during isoflurane anesthesia
Table 3 Summarizes levels of 11 PFC metabolites measured during sleep relative to wakefulness (from (Bourdon et al. 2018)) and during isoflurane anesthesia relative to wakefulness (Table 1)