Litaf

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); negative regulation of non-canonical NF-kappaB signal transduction (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH Experimental Diabetes Mellitus; basal cell carcinoma (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cytoplasmic side of early endosome membrane (ortholog); cytoplasmic side of late endosome membrane (ortholog); cytoplasmic side of lysosomal membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol

编码一种表现出DNA结合转录激活活性的蛋白质，该蛋白质为RNA聚合酶II特异性（同源）；具有相同的蛋白质结合（同源）；RNA聚合酶II顺式调控区序列特异性DNA结合（同源）；参与细胞对脂多糖的应答反应（同源）；非典型NF-kappaB信号转导的负调控（同源）；典型NF-kappaB信号转导的正调控（同源）；与实验性糖尿病、基底细胞癌（同源）、查尔科-马里-图奥特病（同源）相关；存在于早期内质网膜胞浆侧（同源）、晚期内质网膜胞浆侧（同源）、溶酶体膜胞浆侧（同源）；与（+）五味子素B、1,3,5-三硝基-1,3,5-三氮杂环烷、17α-乙炔雌二醇相互作用