Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys cahirinus. Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys cahirinus

This project is a comprehensive analysis of gene expression following full-thickness excisional dermal wounds in the African spiny mouse and the laboratory mouse. Overall design: 8mm excisional wounds were made on the dorsal skin. Wounds were harvested on day 7 and 14 after wounding. Normal, unwounded (day 0) skin was used as a control. N=4 for each time point for each species. 2x150 bp paired-end reads. DSN library was equal amounts of all Acomys samples, pooled, and normalized using duplex-specific nuclease. The 'Mus_Day-0_rep3' sample was removed from downstream analysis due to poor QC results, and is not included here.