Data_Sheet_1_Metabolic Acidosis Is an Independent Risk Factor of Renal Progression in Korean Chronic Kidney Disease Patients: The KNOW-CKD Study Results.docx

Background: We aimed to evaluate serum bicarbonate as a risk factor for renal progression, cardiovascular events, and mortality in Korean CKD patients.Methods: We analyzed 1,808 participants from a Korean CKD cohort whose serum bicarbonate levels were measured at enrollment. Serum bicarbonate levels were categorized as low, lower normal, higher normal, and high (total carbon dioxide背景：本研究旨在评估血清碳酸氢盐作为韩国慢性肾病（CKD）患者肾脏病变进展、心血管事件及死亡率的风险因素。方法：我们对1808名血清碳酸氢盐水平在入组时进行测量的韩国CKD队列参与者进行了分析。血清碳酸氢盐水平被分为低、轻度正常、高度正常和高（总二氧化碳水平）四类。